My lab studies the interplay between the gut microbiome and the immune system and how their “miscues” can lead to autoimmune diseases, particularly type 1...
We are working to understand how cells respond to pathogens, and how these signaling pathways can be harnessed for new potential therapies to treat cancer...
The Lieberman laboratory studies the innate and adaptive immune response to infection and cancer. They seek to understand how cytotoxic T lymphocytes and...
The research efforts in the laboratory are directed towards understanding the molecular basis of pathogenesis of human infections caused by opportunistic...
The Mekalanos laboratory is engaged in the analysis of bacterial virulence and functional genomics. The goal of these studies is to understand how pathogenic... Read more about John Mekalanos
My lab is interested in the structure, dynamics, and function of the cytoskeleton. We use imaging-based assays in living cells and in vitro extracts, in... Read more about Timothy J. Mitchison
in situ single-cell transcriptomic techniques offer the exciting ability to characterize gene expression within single cells in their native tissue context.... Read more about Jeffrey Moffitt
We are interested in mechanisms whereby bacterial pathogens cause disease and in defining and testing immune protective mechanisms relevant to prevention...
Despite the growing recognition of the importance of the microbiota to humans, there are fundamental aspects of the microbiota and its relation to the...
We are interested in the molecular mechanisms by which proteins are transported across the endoplasmic reticulum (ER) membrane. Proteins are transported...
Professor of Biological Chemistry and Molecular Pharmacology
Research in the Roberts laboratory is centered on kinases, kinase inhibitors, and cancer. We work in a variety of model systems and utilize approaches varying... Read more about Thomas McCoy Roberts
Adjunct Professor of Immunology and Infectious Diseases
Despite years of research, tuberculosis remains a leading killer, causing almost two million deaths each year worldwide. While the treatment for drug-...