David Wesley Gaiser Professor of Biological Chemistry and Molecular Pharmacology
Transcriptional regulation in response to environmental and developmental cues is mediated by the combinatorial and synergistic action of specific DNA-...
Within cells macromolecules form complex intertwined networks of functionally interacting components. The molecular mechanisms underlying biological...
A critical step in eukaryotic gene regulation is the control of transcription across the chromatin template. While transcription has been extensively...
Professor of Biological Chemistry and Molecular Pharmacology
We are interested in how kinases in general, and phosphatidylinositol 3-kinases (PI3K) in particular, control malignant transformation. The work of our...
Maintenance of genomic integrity is essential for the survival of all organisms. In humans, loss of genomic integrity is closely linked to cancers and...
