The Jorfi Lab integrates neuroscience, immunology, and bioengineering to uncover how the immune system contributes to neurodegeneration, with a primary focus on Alzheimer’s disease and related disorders. Once thought to be immune-privileged, the brain is...
Chronic pain and headache disorders are two leading causes of disability world-wide. Improving treatments for these conditions is a major focus of my lab as well as my clinical practice as a neurologist. The experience of pain begins with specialized...
We study how Epstein-Barr virus causes nearly 1% of all human cancers and also serves as the major viral trigger for autoimmune diseases, in particular multiple sclerosis.
A fascinating and incompletely understood aspect of EBV pathogenesis is that it...
The Wu laboratory of structural immunology focuses on elucidating the molecular mechanism of signal transduction by immune receptors, especially innate immune receptors. The lab began its studies on the signaling of a classical cytokine produced by the...
Research in the Wolfson lab is focused on understanding how we sense our internal environment. Sensory neurons that innervate internal organs have cell bodies that reside in the dorsal root ganglia, the DRG sensory neurons. These neurons must respond to a...
My lab works at the intersection of virology, immunology and systems biology. Our core mission is to uncover global principles in virology by decoding hundreds of viral genomes. Our projects revolve around a central question: how have the compact genomes...
Our laboratory pursues both basic and translational studies to understand and treat infections caused by intestinal bacteria. Areas of interest described below include the impact of intestinal pathogens on host metabolism and nutrition, development of...
The broad interest of the WAGERS LAB is to identify and analyze tissue-specific stem cell populations in adult animals. This work focuses on understanding the factors controlling the migration and expansion of bone marrow-derived and blood-forming...
The major interest of the Sharpe laboratory is to study functions of T cell costimulatory pathways and their immunoregulatory roles in controlling the balance between T cell activation and tolerance. Costimulation is of therapeutic interest because...
The Rashidian Lab studies cancer immunology and autoimmune disease using expertise in molecular biology, chemical biology and immunology.
