Xin Gu, BBS Faculty Member, Receives Damon Runyon Award

Gu studies how cells regulate the destruction of proteins without using the typical ubiquitin tag, which signals that a protein should be transported to the proteasome for digestion and recycling of amino acids. His lab has discovered a pathway, the midnolin-proteasome pathway, that helps degrade key proteins involved in cancer. Gu is exploring how this pathway might be used to develop new treatments, especially for blood cancers, by targeting specific proteins that drive disease.