Catalog of Mitochondria Across Tree of Life Unearths New Roles for the Cell’s Powerhouse
Survey also suggests new opportunities for treating parasitic infections
- Researchers have built a catalog of mitochondrial proteins found in six eukaryotic organisms — five parasites and one plant — that, along with existing inventories of human and yeast mitochondria, reveals new insights into this essential organelle.
- By highlighting mitochondrial proteins shared by multiple pathogens that are absent in humans, the results suggest new therapeutic targets for neglected tropical diseases.
- Findings from MitoCarta Tree of Life consortium spanning multiple institutions are published in nine related papers.
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