We seek to use the vast knowledge of biology to predictably design biological systems to enhance our fundamental understanding and to provide solutions for real world problems.
Current projects use mammalian cells, simple eukaryotes and prokaryotes....
Mitochondria are tiny organelles found in nearly all cells, serving as the center stage for ATP production, ion homeostasis, and apoptosis. Their composition, density, and coupling efficiency are dynamic properties, varying across cell types and adapting...
My lab is interested in the structure, dynamics, and function of the cytoskeleton. We use imaging-based assays in living cells and in vitro extracts, in conjunction with molecular biology and biochemical fractionation approaches, as well as theory and...
Our lab studies how individual cells translate internal and external signals into decisions such as growth, death, movement or differentiation. We quantitatively measure the changes in level, activity, or localization of proteins in single cells at high...
Our lab has focused on understanding cell morphogenesis, cell proliferation, and cell signaling by combining biochemical, cell biological, and embryological approaches. We are also interested in the evolution of vertebrates through studies of hemichordate...
The Fontana lab has two main goals. First, understand the dynamical processes that constitute and maintain biological organization in terms of interactions among molecular components. Second, identify those properties of a biological system that are...
