Research in the Hwang Laboratory is anchored on the immense phenotypic, temporal and spatial heterogeneity of tumor ecosystems and the many insights that can only be gleaned by studying these systems at the level of their individual components—single...
Certain basic cognitive processes are central to navigating the world around us. Attention, for example is important for almost all of our conscious actions, yet there's so much we still don't know about the cell types and circuits that support it...
The Jorfi Lab integrates neuroscience, immunology, and bioengineering to uncover how the immune system contributes to neurodegeneration, with a primary focus on Alzheimer’s disease and related disorders. Once thought to be immune-privileged, the brain is...
Our laboratory has a broad interest in microbial toxins, bacterial pathogenesis in human/animal/insects, and microbiome. Along these lines of basic research, we are keen in developing microbial protein-inspired novel therapeutics for treating genetic...
Restoring lost function after spinal cord injury or other types of CNS injuries is a major challenge of contemporary neuroscience. A key culprit of functional deficits is the disruption and/or dysfunction of axonal connections connecting different parts...
The brain-CSF interface: Neural stem cells and disease
Defined numbers of neural precursor cells are remarkably synchronized in their task to form the brain, yet no central command coordinating this process has been identified. Neural precursors divide...
We are interested in the fundamental mechanisms of neurodegenerative disorders like Alzheimer’s disease. Over the past century-plus, research has revealed specific proteins that misfold and are deposited in neurodegeneration, and recent discoveries have...
Vik Khurana M.D. Ph.D. is the inaugural incumbent of the Tracy T. Batchelor Endowed Chair in Neurology at MassGeneral Brigham, Chief of the Movement Disorders Division at Brigham and Women's Hospital and Associate Professor of Neurology at Harvard Medical...
We are a collaborative group of genome editing scientists at the Translational Neuroscience Center of Boston Children’s Hospital and Harvard Medical School department of Neurology. We strive to develop gene-based therapeutics for genetic neurological...
