My laboratory is focused on understanding nervous system disease using molecular genetic strategies, beginning with human patients and proceeding through in vitro and modeling studies, with the ultimate goal of improving diagnosis, management and...
Our lab focuses on the molecular nature of innate immune interactions between microbial pathogens and the host. Pathogenic bacteria have evolved complex mechanisms to subvert host cell immune responses and host cell signaling pathways. Our work focuses on...
Research in our laboratory is committed to expanding our molecular understanding of the formation and regeneration of tendons and ligaments. Injuries to tendons and ligaments result in a slow and imperfect regenerative response. In most cases, the...
Our group studies cell death/proliferation signals in relation to development and disease, particularly in skin cancer. We attempt to understand critical modes of cell homeostasis with a goal of molecular targeted therapy as well as prevention of melanoma...
Dr. Daly's lab focuses on computational approaches to understanding the genetics of disease with a strategy of integrating powerful techniques from human and mouse genetics. The lab has extensive experience in linkage and association analysis and has...
Cancer cells display remarkable plasticity allowing them to adapt to ever changing environments. A key feature of this plasticity is their ability to rewire core metabolic networks to provide a steady source of energy and building blocks needed for rapid...
My laboratory employs approaches rooted in synthetic immunology as a means of engineering or enhancing the natural immune system with the goal of understanding, preventing and treating HIV infection. We are currently applying these approaches to a number...
