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An international team led by researchers from Harvard Medical School, Brigham and Women’s Hospital, and the Max Delbrück Center for Molecular Medicine in Germany has created a detailed map of the molecular activity underlying hypertrophic cardiomyopathy...

In mid-August, the drugmakers Moderna and Merck announced that a cancer vaccine trial had successfully lowered risk of both death and metastases of melanoma, a deadly skin cancer. The experimental cancer vaccine, designed to be given to melanoma patients...

More men get prostate cancer in the US than any other form of the disease outside of non-melanoma skin cancer. Around 3.5 million men live with prostate cancer, with 330,000 new diagnoses each year, according to the American Cancer Society. Over 36,000...

Hair-like appendages called motile cilia beat in synchrony on cells in many parts of the body to keep fluids and particles moving along, such as clearing mucus in the lungs so it can be coughed out. Genetic mutations can compromise ciliary structure and...

The way a duo of monkeypox virus proteins change shape as they bind together acts like a switch that starts the process of viral replication, a study led by researchers in the Blavatnik Institute at Harvard Medical School reveals. This kind of detailed...

Meet Brooke & Jason. After her stepfather sustained a spinal cord injury, Brooke became the first woman to skateboard across America, raising more than $55,000 for Wings for Life and for research. Jason became a spinal cord injury (SCI) researcher at...

Scientists have been hard at work for more than 20 years to instruct biological systems, such as E. coli cells, to produce proteins they don’t naturally do. Success could mean faster, cheaper, innovative solutions for medicine, agriculture, materials...

A team led by Harvard Medical School (HMS) researchers is exploring the possibility of creating an entire new class of medicines, with up to $4.4 million in federal funding from the Advanced Research Projects Agency for Health (ARPA-H) under its PROPEL...

Harvard Medical School investigators at Dana-Farber Cancer Institute have developed a new laboratory method for systematically discovering molecular glue degraders — compounds that harness cells’ own waste-disposal machinery to destroy disease-causing...

Cell-communication molecules called kinases play a key role in the growth and spread of many cancers. But exactly which kinases are active in a particular cancer is not always clear — there are 1.8 million sites on human proteins that kinases might act on...